This year’s theme explores how the integration of Artificial Intelligence and the Internet of Things (AIoT) is reshaping industries and daily life. From smart factories and hospitals to sustainable agriculture and energy systems, AIoT is delivering real-time, intelligent solutions that enhance productivity, safety, and quality of life. However, with this transformation come critical challenges in cybersecurity, privacy, and system resilience, requiring advanced technologies like federated learning, blockchain, and homomorphic encryption. Beyond technology, the theme emphasizes the importance of governance, ethics, and inclusive policy frameworks to guide AIoT deployment responsibly. Questions around algorithmic accountability, digital sovereignty, and ethical use of data in areas like elder care and smart cities are central to the conversation. The 2025 IEEE GCAIoT highlights the need for multi-stakeholder dialogue to ensure that AIoT innovations serve human values, promote equity, and support a sustainable, human-centered future